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Meig1tm1.1Zzha
Targeted Allele Detail
Summary
Symbol: Meig1tm1.1Zzha
Name: meiosis expressed gene 1; targeted mutation 1.1, Zhibing Zhang
MGI ID: MGI:4367077
Synonyms: Meig1flox
Gene: Meig1  Location: Chr2:3410080-3423685 bp, - strand  Genetic Position: Chr2, 1.92 cM
Alliance: Meig1tm1.1Zzha page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:153677
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation details: A loxP site was inserted upstream of exon 1, and an frt flanked neo cassette with a 3' loxP site downstream of exon 1. Germ line, flp mediated recombination removed the neo cassette leaving exon 1 floxed. (J:153677)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Meig1 Mutation:  14 strains or lines available
References
Original:  J:153677 Zhang Z, et al., MEIG1 is essential for spermiogenesis in mice. Proc Natl Acad Sci U S A. 2009 Oct 6;106(40):17055-60
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory