Meig1<tm1.2Zzha> Targeted Allele Detail MGI Mouse (MGI:4367078)

Meig1^tm1.2Zzha
Targeted Allele Detail

Summary

Symbol:	Meig1^tm1.2Zzha
Name:	meiosis expressed gene 1; targeted mutation 1.2, Zhibing Zhang
MGI ID:	MGI:4367078
Gene:	Meig1 Location: Chr2:3410080-3423685 bp, - strand Genetic Position: Chr2, 1.92 cM
Alliance:	Meig1^tm1.2Zzha page

Sperm abnormalities in Meig1^tm1.2Zzha/Meig1^tm1.2Zzha mice

Show the 2 phenotype image(s) involving this allele.

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:153677
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Mutation
description

Allele Type:		Targeted (Null/knockout)
Mutations:		Insertion, Intragenic deletion
		Mutation details: Germ line, cre mediated recombination removed exon 1. The absence of protein expression was confirmed by western blot analysis on testes extracts. (J:153677)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Meig1 Mutation:	14 strains or lines available

References

Original:	J:153677 Zhang Z, et al., MEIG1 is essential for spermiogenesis in mice. Proc Natl Acad Sci U S A. 2009 Oct 6;106(40):17055-60
All:	4 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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