Tg(Gfap-cre/PGR*)473Gkl
Transgene Detail
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| Symbol: |
Tg(Gfap-cre/PGR*)473Gkl |
| Name: |
transgene insertion 473, George Kollias |
| MGI ID: |
MGI:4367775 |
| Synonyms: |
GFAP-CrePR, Tg(Gfap-cre/PGR)473Gkl, Tg(GFAP-cre,PGR)473Gkl |
| Transgene: |
Tg(Gfap-cre/PGR*)473Gkl Location: unknown
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| Alliance: |
Tg(Gfap-cre/PGR*)473Gkl page
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| Strain of Origin: |
CBA x C57BL/6
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| Transgene Type: |
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Transgenic (Inducible, Recombinase) |
| Inducer: |
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mifepristone |
| Mutation: |
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Insertion
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Tg(Gfap-cre/PGR*)473Gkl expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| mouse |
Gfap (MGI:95697) |
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Mutation details: This transgene contains the mouse glial fibrillary acidic protein promoter driving the expression of an RU486-inducible Cre recombinase. The encoded protein is a fusion of Cre recombinase with a mutant human progesterone receptor that fails to bind to its natural ligand at physiologic concentrations but does bind to the synthetic progesterone analog RU486. The unbound fusion protein is restricted to the cytoplasm; it can enter the nucleus only when bound to RU486.
(J:115216)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Gfap
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:115216 MUGEN, Information obtained from the Network of Excellence in Integrated Functional Genomics in Mutant Mouse Models as tools to investigate the complexity of Human Immunological Disease (MUGEN). Unpublished. 2006-2015; |
| All: |
1 reference(s) |
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Analysis Tools
