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Tfap2etm1(cre)Will
Targeted Allele Detail
Summary
Symbol: Tfap2etm1(cre)Will
Name: transcription factor AP-2, epsilon; targeted mutation 1, Trevor Williams
MGI ID: MGI:4398845
Synonyms: Tcfap2eak
Gene: Tfap2e  Location: Chr4:126609799-126630033 bp, - strand  Genetic Position: Chr4, 60.91 cM
Alliance: Tfap2etm1(cre)Will page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:154236
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Recombinase)
Mutation:    Insertion
 
Tfap2etm1(cre)Will expression driven by 1 gene
 
Mutation detailsAn IRES, cre, and frt flanked neo cassette were inserted into exon 4. Cre expression is detected in the olfactory bulb. Reduced endogenous transcript expression and cre transcript expression were confirmed by in situ hybridization. (J:154236)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Tfap2e (mouse)
Summary of all recombinase alleles driven by Tfap2e.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 23 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tfap2e Mutation:  10 strains or lines available
References
Original:  J:154236 Feng W, et al., Disorganized olfactory bulb lamination in mice deficient for transcription factor AP-2epsilon. Mol Cell Neurosci. 2009 Nov;42(3):161-71
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory