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Or13c7ctm1.1(cre)Jgst
Targeted Allele Detail
Summary
Symbol: Or13c7ctm1.1(cre)Jgst
Name: olfactory receptor family 13 subfamily C member 7C; targeted mutation 1.1, Jorg Strotmann
MGI ID: MGI:4398872
Synonyms: 37CCre*-F
Gene: Or13c7c  Location: Chr4:43834752-43837643 bp, - strand  Genetic Position: Chr4, 23.05 cM
Alliance: Or13c7ctm1.1(cre)Jgst page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:154249
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Or13c7ctm1.1(cre)Jgst expression driven by 1 gene
 
Mutation detailsThe targeting construct contained a cassette encoding an IRES-cre sequence followed by an frt-flanked neo selection marker. The construct was targeted to a position 3 nucleotides downstream of the Olfr157 coding sequence. After linearization the construct was injected into R1 ES cells. Clones were injected into C57BL/6J blastocysts and germline transmission was obtained. These mice were crossed to mice expressing flp recombinase to remove the frt-neo-frt sequence to ascertain if its presence induced an artfacts in the observed expression of the allele. (J:154249)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Or13c7c (mouse)
Summary of all recombinase alleles driven by Or13c7c.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Or13c7c Mutation:  11 strains or lines available
References
Original:  J:154249 Strotmann J, et al., The patch-like pattern of OR37 receptors is formed by turning off gene expression in non-appropriate areas. Mol Cell Neurosci. 2009 Aug;41(4):474-85
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/03/2024
MGI 6.24
The Jackson Laboratory