Tg(Slc16a8-cre/ERT2,-EGFP)1Moss
Transgene Detail
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| Symbol: |
Tg(Slc16a8-cre/ERT2,-EGFP)1Moss |
| Name: |
transgene insertion 1, Steven E Moss |
| MGI ID: |
MGI:4399744 |
| Synonyms: |
RPECreER |
| Transgene: |
Tg(Slc16a8-cre/ERT2,-EGFP)1Moss Location: unknown
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| Alliance: |
Tg(Slc16a8-cre/ERT2,-EGFP)1Moss page
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| Strain of Origin: |
C57BL/6 x CBA
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| Transgene Type: |
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Transgenic (Inducible, Recombinase, Reporter) |
| Inducer: |
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tamoxifen |
| Mutation: |
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Insertion
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Tg(Slc16a8-cre/ERT2,-EGFP)1Moss expression driven by
1 gene
Transgene expression driven by:
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Mutation details: The transgene was constructed from a modification of BAC RP24-149-K18 such that a cassette containing an improved cre gene fused to the modified human ESR1 receptor (ERT2) and an IRES-EGFP followed by an frt-flanked neo cassette was inserted at the start of the Slc16a8 open reading frame. Transient flp expression in removed the neo cassette in bacterial cells. Cre activity is detected in the retinal pigment epithelium.
(J:154671)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Slc16a8
(mouse)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:154671 Longbottom R, et al., Genetic ablation of retinal pigment epithelial cells reveals the adaptive response of the epithelium and impact on photoreceptors. Proc Natl Acad Sci U S A. 2009 Nov 3;106(44):18728-33 |
| All: |
1 reference(s) |
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Analysis Tools
