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Tg(Grm6-icre)1Rlbn
Transgene Detail
Summary
Symbol: Tg(Grm6-icre)1Rlbn
Name: transgene insertion 1, R Lane Brown
MGI ID: MGI:4411993
Synonyms: mGluR6-Cre
Transgene: Tg(Grm6-icre)1Rlbn  Location: unknown  
Alliance: Tg(Grm6-icre)1Rlbn page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Grm6-icre)1Rlbn expression driven by 1 gene
 
Mutation details: The transgenic construct contains a 637-bp Grm6 (mGluR6) promoter fragment upstream of a codon-improved cre (iCre) and a polyadenylation sequence. A 9.5 kb fragment of the Grm6 5' upstream region was inserted to reconstitute the full-length Grm6 promoter. The construct was injected into fertilized oocytes and two founder lines were obtained. Only one line was found to express cre in the retina. (J:154776)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Grm6 (mouse)
Summary of all recombinase alleles driven by Grm6.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:154776 Morgans CW, et al., TRPM1 is required for the depolarizing light response in retinal ON-bipolar cells. Proc Natl Acad Sci U S A. 2009 Nov 10;106(45):19174-8
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory