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Wnt8btm1Jmas
Targeted Allele Detail
Summary
Symbol: Wnt8btm1Jmas
Name: wingless-type MMTV integration site family, member 8B; targeted mutation 1, John Mason
MGI ID: MGI:4414945
Gene: Wnt8b  Location: Chr19:44481912-44502712 bp, + strand  Genetic Position: Chr19, 37.98 cM
Alliance: Wnt8btm1Jmas page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:155332
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 4 and 5 and most of the coding region contained within exon 6 were replaced with a neo cassette. The absence of transcript expression was confirmed by RT-PCR and in situ hybridization. (J:155332)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Wnt8b Mutation:  17 strains or lines available
References
Original:  J:155332 Fotaki V, et al., Loss of Wnt8b has no overt effect on hippocampus development but leads to altered Wnt gene expression levels in dorsomedial telencephalon. Dev Dyn. 2010 Jan;239(1):284-96
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory