Tg(Prnp-cre/ERT)28.8Ics Transgene Detail MGI Mouse (MGI:4415180)

Tg(Prnp-cre/ERT)28.8Ics
Transgene Detail

Summary

Symbol:	Tg(Prnp-cre/ERT)28.8Ics
Name:	transgene insertion 28.8, Mouse Clinical Institute
MGI ID:	MGI:4415180
Synonyms:	PrpCreER, PrP-Cre-ER^T 28.8, PrP-Cre-ER^T28.8^(tg/0)
Transgene:	Tg(Prnp-cre/ERT)28.8Ics Location: unknown
Alliance:	Tg(Prnp-cre/ERT)28.8Ics page

Transgene
origin

Strain of Origin:

(C57BL/6 x SJL)F1

Transgene
description

Transgene Type:

Transgenic (Inducible, Recombinase)

Inducer:

tamoxifen

Mutation:

Insertion

Tg(Prnp-cre/ERT)28.8Ics expression driven by 1 gene

Mutation details: The mouse prion promoter was used to drive the expression of the tamoxifen-inducible form of a Cre recombinase/estrogen receptor fusion protein. Ten transgenic founder lines (28.1-28.10) that transmitted the transgene were obtained. Lines 28.4, 28.6, and 28.8 were further characterized. (J:81569)

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Prnp (mouse) Summary of all recombinase alleles driven by Prnp. Comparative matrix view of recombinase activities Alliance mouse Prnp gene page

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

Original:	J:81392 Weber P, et al., Temporally controlled site-specific mutagenesis in the germ cell lineage of the mouse testis. Biol Reprod. 2003 Feb;68(2):553-9
All:	3 reference(s)

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