Tg(Pgk1-flpo)10Sykr
Transgene Detail
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| Symbol: |
Tg(Pgk1-flpo)10Sykr |
| Name: |
transgene insertion 10, Shoshana Yakar |
| MGI ID: |
MGI:4415609 |
| Synonyms: |
FLPo-10 |
| Transgene: |
Tg(Pgk1-flpo)10Sykr Location: unknown
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| Alliance: |
Tg(Pgk1-flpo)10Sykr page
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| Strain of Origin: |
C57BL/6 x C3H
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| Transgene Type: |
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Transgenic (Recombinase) |
| Mutation: |
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Insertion
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Tg(Pgk1-flpo)10Sykr expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| Not Specified |
Pgk1 |
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Mutation details: A transgenic construct was created with the Pgk1 promoter driving mouse codon-optimized FLP (FLPo) recombinase. The linearized construct was injected into fertilized C57BL/6 x C3H oocytes. Six founder mice showing germline transmission were generated. These animals demostrated FLP expression as early as 3.5 embryonic days and adults displayed ubiquitious expression in all tissues examined with strongest expression in the testis and ovary. Line 10 showed 100% recombination efficiency when crossed to mice expressing a Ghr allele with a FRT-flanked PGK-Neo cassette in intron 5. (This Ghr allele is the parent construct of the Ghrtm1.1Masp allele.)
(J:154848, J:240544)
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Schematic of the Tg(Pgk1-flpo)10Sykr transgene |
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Pgk1
(species not specified)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:154848 Wu Y, et al., High-efficient FLPo deleter mice in C57BL/6J background. PLoS One. 2009;4(11):e8054 |
| All: |
99 reference(s) |
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Analysis Tools
