Tg(CAG-flpe)37Ito
Transgene Detail
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Symbol: |
Tg(CAG-flpe)37Ito |
Name: |
transgene insertion 37, Shigeyoshi Itohara |
MGI ID: |
MGI:4415709 |
Synonyms: |
CAG-FLPe deleter, Tg-CAG_FLPe37 |
Transgene: |
Tg(CAG-flpe)37Ito Location: unknown
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Alliance: |
Tg(CAG-flpe)37Ito page
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Transgene Type: |
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Transgenic (Recombinase) |
Mutation: |
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Insertion
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Tg(CAG-flpe)37Ito expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
chicken |
CAG |
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Mutation details: The CAG promoter (chicken beta-actin promoter with CMV enhancers) was used to drive expression of a gene encoding nuclear localized FLPe recombinase. Five founder lines were established (lines 16, 32, 36, 37 and 41), of which lines 16, 32 and 36 exhibited 100% recombination when crossed to a mouse bearing a frt-flanked cassette; 10/11 mice of line 37 showed recombination. Mosaicism was noted in 2/9 of line 16 and in 1/8 of line 32 double transgenic mice.
(J:108559)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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CAG
(chicken)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:108559 Kanki H, et al., High-efficiency CAG-FLPe deleter mice in C57BL/6J background. Exp Anim. 2006 Apr;55(2):137-41 |
All: |
16 reference(s) |
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