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Tg(CAG-flpe)37Ito
Transgene Detail
Summary
Symbol: Tg(CAG-flpe)37Ito
Name: transgene insertion 37, Shigeyoshi Itohara
MGI ID: MGI:4415709
Synonyms: CAG-FLPe deleter, Tg-CAG_FLPe37
Transgene: Tg(CAG-flpe)37Ito  Location: unknown  
Alliance: Tg(CAG-flpe)37Ito page
Transgene
origin
Strain of Origin:  C57BL/6JJcl
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(CAG-flpe)37Ito expression driven by 1 gene
 
Mutation detailsThe CAG promoter (chicken beta-actin promoter with CMV enhancers) was used to drive expression of a gene encoding nuclear localized FLPe recombinase. Five founder lines were established (lines 16, 32, 36, 37 and 41), of which lines 16, 32 and 36 exhibited 100% recombination when crossed to a mouse bearing a frt-flanked cassette; 10/11 mice of line 37 showed recombination. Mosaicism was noted in 2/9 of line 16 and in 1/8 of line 32 double transgenic mice. (J:108559)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: CAG (chicken)
Summary of all recombinase alleles driven by CAG.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:108559 Kanki H, et al., High-efficiency CAG-FLPe deleter mice in C57BL/6J background. Exp Anim. 2006 Apr;55(2):137-41
All:  16 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory