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Cr2tm1.1Jhws
Targeted Allele Detail
Summary
Symbol: Cr2tm1.1Jhws
Name: complement receptor 2; targeted mutation 1.1, John Weiss
MGI ID: MGI:4417922
Synonyms: Cr2idelta
Gene: Cr2  Location: Chr1:194819119-194859024 bp, - strand  Genetic Position: Chr1, 98.44 cM
Alliance: Cr2tm1.1Jhws page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:155241
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsGenomic sequence spanning 1726 bp of intron 1, containing the MH box sequences, was replaced with a self-excising neomycin resistance (neo) cassette. The neo cassette removed itself. RT-PCR analysis confirmed the normal expression of the CR1 and CR2 transcripts. (J:155241)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cr2 Mutation:  84 strains or lines available
References
Original:  J:155241 Roundy KM, et al., Deletion of putative intronic control sequences does not alter cell or stage specific expression of Cr2. Mol Immunol. 2009 Dec;47(2-3):517-25
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory