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Tg(TNNI2-icre)1Vrmn
Transgene Detail
Summary
Symbol: Tg(TNNI2-icre)1Vrmn
Name: transgene insertion 1, Holly Van Remmen
MGI ID: MGI:4418328
Synonyms: TnIFastCre
Transgene: Tg(TNNI2-icre)1Vrmn  Location: unknown  
Alliance: Tg(TNNI2-icre)1Vrmn page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(TNNI2-icre)1Vrmn expression driven by 1 gene
 
Mutation detailsThe transgene construct included 530 bp of 5'-flanking quail TnIFast (TNNI2) gene sequence (promter), exon 1, intron 1 containing the IRE-enhancer, and the untranslated exon 2 sequence up to the ATG initiation codon. The improved cre (icre) coding sequence replaced exon 2 sequences downstream of the ATG and was linked to the SV40 splicing and polyadenylation signals. (J:155917)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: TNNI2 (species not specified)
Summary of all recombinase alleles driven by TNNI2.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:155917 Lustgarten MS, et al., Conditional knockout of Mn-SOD targeted to type IIB skeletal muscle fibers increases oxidative stress and is sufficient to alter aerobic exercise capacity. Am J Physiol Cell Physiol. 2009 Dec;297(6):C1520-32
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory