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Myd88tm1.1Defr
Targeted Allele Detail
Summary
Symbol: Myd88tm1.1Defr
Name: myeloid differentiation primary response gene 88; targeted mutation 1.1, Anthony L DeFranco
MGI ID: MGI:4421295
Gene: Myd88  Location: Chr9:119165000-119169084 bp, - strand  Genetic Position: Chr9, 71.33 cM
Alliance: Myd88tm1.1Defr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:139001
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation details: Mice carrying the Myd88tm1Defr allele were crossed with Tg(Zp3-cre)93Knw mice to remove exon 3. (J:139001)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Myd88 Mutation:  52 strains or lines available
References
Original:  J:139001 Hou B, et al., Toll-like Receptors Activate Innate and Adaptive Immunity by using Dendritic Cell-Intrinsic and -Extrinsic Mechanisms. Immunity. 2008 Aug;29(2):272-82
All:  317 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory