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Lmo4tm1Gan
Targeted Allele Detail
Summary
Symbol: Lmo4tm1Gan
Name: LIM domain only 4; targeted mutation 1, Lin Gan
MGI ID: MGI:4421413
Synonyms: Lmo4lacZ
Gene: Lmo4  Location: Chr3:143894291-143910981 bp, - strand  Genetic Position: Chr3, 68.61 cM
Alliance: Lmo4tm1Gan page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:156733
Parent Cell Line:  W4 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: Exon 2 and part of intron 2 were replaced with a lacZ gene. X-gal staining confirmed lacZ expression in E9.5 embryos. Immunolabeling confirmed the absence of endogenous protein expression at E10.5 in the ear. (J:156733)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 7 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lmo4 Mutation:  9 strains or lines available
References
Original:  J:156733 Deng M, et al., Requirement for Lmo4 in the vestibular morphogenesis of mouse inner ear. Dev Biol. 2010 Feb 1;338(1):38-49
All:  4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory