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Insl6tm1Imad
Targeted Allele Detail
Summary
Symbol: Insl6tm1Imad
Name: insulin-like 6; targeted mutation 1, Ibrahim M Adham
MGI ID: MGI:4431170
Gene: Insl6  Location: Chr19:29298754-29302718 bp, - strand  Genetic Position: Chr19, 23.82 cM, cytoband C3
Alliance: Insl6tm1Imad page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:157348
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: Exon 1 was replaced with a neo cassette. The absence of transcript expression was confirmed by RT-PCR in testis extracts. (J:157348)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 16 assay results
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Insl6 Mutation:  9 strains or lines available
References
Original:  J:157348 Burnicka-Turek O, et al., Inactivation of insulin-like factor 6 disrupts the progression of spermatogenesis at late meiotic prophase. Endocrinology. 2009 Sep;150(9):4348-57
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory