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Is(17B1)1Yah
Targeted Allele Detail
Summary
Symbol: Is(17B1)1Yah
Name: insertion, Chr 17, cytogenetic band B1, Yann Herault 1
MGI ID: MGI:4431358
Synonyms: Is1Yah, U2af1tm1Yah
Gene: Is(17B1)1Yah  Location: unknown  Genetic Position: Chr17, Syntenic
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:154298
Parent Cell Line:  HM-1 (ES Cell)
Strain of Origin:  129P2/OlaHsd-Hprt1b-m3
Mutation
description
Allele Type:    Targeted (Reporter)
Mutation:    Insertion
 
Mutation detailsA MICER clone was identified that contained the insertion of 3' Hprt mini gene, loxP, and puro cassette between Cbs and U2af1. It was produced in cis with an insertion of a 5' Hprt mini gene, loxP site, and puro cassette in Abcg1 (Abcg1tm1Yah) 0.59 Mb away. (J:154298)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Is(17B1)1Yah Mutation:  1 strain or line available
References
Original:  J:154298 Pereira PL, et al., A new mouse model for the trisomy of the Abcg1-U2af1 region reveals the complexity of the combinatorial genetic code of down syndrome. Hum Mol Genet. 2009 Dec 15;18(24):4756-4769
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory