Is(14)1Rdf Targeted Allele Detail MGI Mouse (MGI:4437012)

Is(14)1Rdf
Targeted Allele Detail

Summary

Symbol:	Is(14)1Rdf
Name:	insertion, Chr 14, Riccardo Dalla-Favera 1
MGI ID:	MGI:4437012
Gene:	Is(14)1Rdf Location: unknown Genetic Position: Chr14, Syntenic

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:156946
Parent Cell Line:	W9.5/W95 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation
description

Allele Type:		Targeted (Conditional ready, No functional change)
Mutation:		Insertion
		Mutation details: LoxP and FRT sites as well as a Neo cassette and EGFP coding sequence were placed approximately 20 kb centromeric to Trim13 by homologous recombination. (J:156946)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Disease models

Tumor Data

List all tumor models in MMHCdb carrying Is(14)1Rdf

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Is(14)1Rdf Mutation:	0 strains or lines available

References

Original:	J:156946 Klein U, et al., The DLEU2/miR-15a/16-1 Cluster Controls B Cell Proliferation and Its Deletion Leads to Chronic Lymphocytic Leukemia. Cancer Cell. 2010 Jan 19;17(1):28-40
All:	2 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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