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Foxd1tm2(GFP/cre/ERT2)Amc
Targeted Allele Detail
Summary
Symbol: Foxd1tm2(GFP/cre/ERT2)Amc
Name: forkhead box D1; targeted mutation 2, Andrew P McMahon
MGI ID: MGI:4437895
Synonyms: FoxD1-GCE
Gene: Foxd1  Location: Chr13:98490753-98493213 bp, + strand  Genetic Position: Chr13, 51.96 cM
Alliance: Foxd1tm2(GFP/cre/ERT2)Amc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:158051
Parent Cell Line:  v6.5 (ES Cell)
Strain of Origin:  (C57BL/6 x 129S4/SvJae)F1
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase, Reporter)
Inducer:    tamoxifen
Mutation:    Insertion
 
Foxd1tm2(GFP/cre/ERT2)Amc expression driven by 1 gene
 
Mutation details: A targeting vector was designed to insert an eGFP/Cre/ERT2 (GCE) fusion protein coding sequence and frt-flanked PGKneobpA selection cassette into the initiation codon of the Forkhead box D1 (Foxd1) targeted gene. (J:158051)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Foxd1 (mouse)
Summary of all recombinase alleles driven by Foxd1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Foxd1 Mutation:  13 strains or lines available
References
Original:  J:158051 Humphreys BD, et al., Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis. Am J Pathol. 2010 Jan;176(1):85-97
All:  8 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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11/12/2024
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