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Tg(Myl1-cre)1Sjl
Transgene Detail
Summary
Symbol: Tg(Myl1-cre)1Sjl
Name: transgene insertion 1, Sejin Lee
MGI ID: MGI:4438603
Synonyms: MLC-Cre
Transgene: Tg(Myl1-cre)1Sjl  Location: unknown  
Alliance: Tg(Myl1-cre)1Sjl page
Transgene
origin
Strain of Origin:  (C57BL/6J x SJL/J)F1
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Myl1-cre)1Sjl expression driven by 1 gene
 
Mutation details: From 5' to 3' the tansgene contains a synthetic polyadenylation site, the rat myosin light chain 1 gene promoter, the cre recombinase gene modified to contain a Kozak consensus site immediately upstream of the start codon, intron and polyadenylation sites from the SV40 t antigen gene, and the rat myosin light chain 1/3 enhancer. A line was chosen that exhibited skeletal muscle-specific expression as determined by Northern analysis. (J:158173)
Schematic of the Tg(Myl1-cre)1Sjl transgene
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Myl1 (rat)
Summary of all recombinase alleles driven by Myl1.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:158173 McPherron AC, et al., Redundancy of myostatin and growth/differentiation factor 11 function. BMC Dev Biol. 2009;9:24
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory