Tg(Flt4-cre)44Ichi
Transgene Detail
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| Symbol: |
Tg(Flt4-cre)44Ichi |
| Name: |
transgnene insertion 44, Hirotake Ichise |
| MGI ID: |
MGI:4441403 |
| Synonyms: |
Vegfr3-Cre |
| Transgene: |
Tg(Flt4-cre)44Ichi Location: unknown
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| Alliance: |
Tg(Flt4-cre)44Ichi page
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| Transgene Type: |
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Transgenic (Recombinase) |
| Mutation: |
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Insertion
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Tg(Flt4-cre)44Ichi expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| mouse |
Flt4 (MGI:95561) |
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Mutation details: A cDNA encoding nlscre was inserted after 7 kb fragment of the Flt4 (Vegfr3) gene promoter region from the BAC RPC123-118J11 in the targeting vector. The cre sequence was followed by a polyA signal sequence from the murine Pgk gene. This vector was purified and injected into pronuclei of fertilized C57BL/6J mice. Line 44 showed recombination in lymphatic endothelial cells when crossed to reporter mice.
(J:159024)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Flt4
(mouse)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:159024 Ichise T, et al., H-, N- and Kras cooperatively regulate lymphatic vessel growth by modulating VEGFR3 expression in lymphatic endothelial cells in mice. Development. 2010 Mar;137(6):1003-13 |
| All: |
2 reference(s) |
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Analysis Tools
