Prkra<lear> Spontaneous Allele Detail MGI Mouse (MGI:4442387)

Prkra^lear
Spontaneous Allele Detail

Summary

Symbol:	Prkra^lear
Name:	protein kinase, interferon inducible double stranded RNA dependent activator; little ears
MGI ID:	MGI:4442387
Gene:	Prkra Location: Chr2:76460242-76478359 bp, - strand Genetic Position: Chr2, 45.07 cM
Alliance:	Prkra^lear page

Small ears and smaller body size of Prkra^lear/Prkra^lear female (left) compared to heterozygote (right) at nine weeks of age

Show the 1 phenotype image(s) involving this allele.

Mutation
origin

Strain of Origin:

C57BL/6J

Mutation
description

Allele Type:		Spontaneous
Mutation:		Single point mutation
		Mutation details: This spontaneous mutation has a T-to-A transversion at chromosome 2:76,639,197 (GRCm38) in intron 5 immediately adjacent to the conserved splice donor site. (J:176116, J:222308, J:223062)
Inheritance:		Recessive

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Structures Affected by this Mutation:

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Prkra Mutation:	24 strains or lines available

References

Original:	J:159349 Curtain MM, et al., An Ear Pinna Mutation in the Mouse on Chromosome Two. MGI Direct Data Submission. 2010;
All:	5 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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