Rr94tm3.1Litt
Targeted Allele Detail
|
|
| Symbol: |
Rr94tm3.1Litt |
| Name: |
regulatory region 94; targeted mutation 3.1, Dan R Littman |
| MGI ID: |
MGI:4452050 |
| Synonyms: |
Cd4E4pFL, Cd4tm3.1Litt, E4PF |
| Gene: |
Rr94 Location: unknown Genetic Position: Chr6, Syntenic
|
| Alliance: |
Rr94tm3.1Litt page
|
|
| Germline Transmission: |
Earliest citation of germline transmission:
J:158962
|
| Parent Cell Line: |
E14 (ES Cell)
|
| Strain of Origin: |
129P2/OlaHsd
|
|
| Allele Type: |
|
Targeted (Conditional ready, Modified regulatory region, No functional change) |
| Mutation: |
|
Insertion
|
| |
|
Mutation details: Proximal enhancer E4p upstream of Cd4 exon 1 was flanked by a loxP site and a floxed neomycin resistance gene cassette. Cre-mediated recombination removed the neo cassette leaving the enhancer floxed.
(J:158962)
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
| Carrying any Rr94 Mutation: |
0 strains or lines available
|
|
| Original: |
J:158962 Chong MM, et al., Epigenetic propagation of CD4 expression is established by the Cd4 proximal enhancer in helper T cells. Genes Dev. 2010 Apr 1;24(7):659-69 |
| All: |
2 reference(s) |
|
Analysis Tools
