Tg(CAG-flpo)1Afst
Transgene Detail
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| Symbol: |
Tg(CAG-flpo)1Afst |
| Name: |
transgene insertion 1, A Francis Stewart |
| MGI ID: |
MGI:4453967 |
| Synonyms: |
CAGGs-Flpo, Flpo |
| Transgene: |
Tg(CAG-flpo)1Afst Location: unknown
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| Alliance: |
Tg(CAG-flpo)1Afst page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:160215
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| Parent Cell Line: |
JM8.F6 (ES Cell)
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| Strain of Origin: |
C57BL/6N
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| Transgene Type: |
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Transgenic (Recombinase) |
| Mutation: |
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Insertion
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Tg(CAG-flpo)1Afst expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| chicken |
CAG |
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Mutation details: A linearized plasmid encoding the CAGGs promoter driving a codon optimized Flp recombinase (Flpo) and an IRES-puromycin sequence was introduced into JM8.F6 ES cells. Two clones were injected into 8-cell C57BL/6 albino embryos. One chimera showed germline transmission when crossed to C57BL/6 albino animals.
(J:160215)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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CAG
(chicken)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 3 strains available
Cell Lines: 0 lines available
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| Original: |
J:160215 Kranz A, et al., An improved Flp deleter mouse in C57Bl/6 based on Flpo recombinase. Genesis. 2010 Aug;48(8):512-20 |
| All: |
69 reference(s) |
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Analysis Tools
