Lcmt1tm1e(EUCOMM)Hmgu
Targeted Allele Detail
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| Symbol: |
Lcmt1tm1e(EUCOMM)Hmgu |
| Name: |
leucine carboxyl methyltransferase 1; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH |
| MGI ID: |
MGI:4455788 |
| Gene: |
Lcmt1 Location: Chr7:122977026-123029581 bp, + strand Genetic Position: Chr7, 67.42 cM
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| IMPC: |
Lcmt1 gene page |
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| Mutant Cell Lines: |
HEPD0629_7_A09, HEPD0629_7_A11, HEPD0629_7_A12, HEPD0629_7_B10, HEPD0629_7_C10, HEPD0629_7_D10, HEPD0629_7_D11, HEPD0629_7_E09, HEPD0629_7_E10, HEPD0629_7_F09, HEPD0629_7_F10, HEPD0629_7_G09, HEPD0629_7_G12, HEPD0629_7_H10, HEPD0629_7_H11 |
| Germline Transmission: |
Unknown
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| Parent Cell Line: |
JM8A3.N1 (ES Cell)
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| Strain of Origin: |
C57BL/6N-Atm1Brd
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| Project Collection: |
EUCOMM
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| Allele Type: |
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Targeted (Null/knockout, Reporter) |
| Mutation: |
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Insertion
Vector: L1L2_Bact_P
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Mutation details: The L1L2_Bact_P cassette was inserted at position 123000209 of Chromosome 7 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
(J:157065)
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| Original: |
J:157065 Helmholtz Zentrum Muenchen GmbH, Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu). MGI Direct Data Submission. 2010-2015; |
| All: |
1 reference(s) |
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Analysis Tools
