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Sufutm1.1Blnw
Targeted Allele Detail
Summary
Symbol: Sufutm1.1Blnw
Name: SUFU negative regulator of hedgehog signaling; targeted mutation 1.1, Baolin Wang
MGI ID: MGI:4461193
Gene: Sufu  Location: Chr19:46385335-46477243 bp, + strand  Genetic Position: Chr19, 38.85 cM
Alliance: Sufutm1.1Blnw page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:161408
Parent Cell Line:  W4 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Cre mediated recombination removed the neo cassette and exon 1. (J:161408)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 4 assay results
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sufu Mutation:  59 strains or lines available
References
Original:  J:161408 Wang C, et al., Suppressor of fused and Spop regulate the stability, processing and function of Gli2 and Gli3 full-length activators but not their repressors. Development. 2010 Jun;137(12):2001-9
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory