Ar<tm2Ska> Targeted Allele Detail MGI Mouse (MGI:4461236)

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Ar^tm2Ska
Targeted Allele Detail

Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Summary

Symbol:	Ar^tm2Ska
Name:	androgen receptor; targeted mutation 2, Shigeaki Kato
MGI ID:	MGI:4461236
Synonyms:	AR^L2, Ar^lox
Gene:	Ar Location: ChrX:97192375-97366821 bp, + strand Genetic Position: ChrX, 42.82 cM
Alliance:	Ar^tm2Ska page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:85484
Parent Cell Line:	TT2 (ES Cell)
Strain of Origin:	(C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation
description

Allele Type:		Targeted (Conditional ready, No functional change)
Mutation:		Insertion
		Mutation details: A loxP site was inserted upstream of exon 1 and a floxed neomycin resistance cassette was introduced downstream. This allele was used to generate Ar^tm1Ska. (J:85484)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Ar Mutation:	23 strains or lines available

References

Original:	J:85484 Matsumoto T, et al., Androgen receptor functions from reverse genetic models. J Steroid Biochem Mol Biol. 2003 Jun;85(2-5):95-9
All:	15 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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