Tg(Adipoq-cre)#Pesch
Transgene Detail
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| Symbol: |
Tg(Adipoq-cre)#Pesch |
| Name: |
transgene insertion, Philipp E Scherer |
| MGI ID: |
MGI:4462047 |
| Synonyms: |
5.4-kb Cre |
| Transgene: |
Tg(Adipoq-cre)#Pesch Location: unknown
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| Alliance: |
Tg(Adipoq-cre)#Pesch page
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| Transgene Type: |
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Transgenic (Recombinase) |
| Mutation: |
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Insertion
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Tg(Adipoq-cre)#Pesch expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| Not Specified |
Adipoq |
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Mutation details: A 5.4-kb promoter construct containing a 4.9-kb upstream adiponectin promoter sequence, the first exon, 200 bp from the 5' end of intron 1, 200 bp from the 3' end of intron 1, and a partial fragment of the second exon was generated. The endogenous ATG in the exon 2 fragment was mutated to ATA to facilitate correct translation initiation of the transgene. The construct was fused to the cre recombinase open reading frame and the linearized fragment was microinjected into FVB pronuclei. Founders were backcrossed to FVB mice. No line numbers were specified.
(J:160881)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Adipoq
(species not specified)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:160881 Wang ZV, et al., Identification and characterization of a promoter cassette conferring adipocyte-specific gene expression. Endocrinology. 2010 Jun;151(6):2933-9 |
| All: |
20 reference(s) |
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Analysis Tools
