Gata2<tm1Msal> Targeted Allele Detail MGI Mouse (MGI:4818492)

Gata2^tm1Msal
Targeted Allele Detail

Summary

Symbol:	Gata2^tm1Msal
Name:	GATA binding protein 2; targeted mutation 1, Marjo Salminen
MGI ID:	MGI:4818492
Synonyms:	Gata2^c, Gata2^flox
Gene:	Gata2 Location: Chr6:88170873-88184014 bp, + strand Genetic Position: Chr6, 39.2 cM
Alliance:	Gata2^tm1Msal page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:143527
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation
description

Allele Type:		Targeted (Conditional ready, No functional change)
Mutation:		Insertion
		Mutation details: A loxP site was inserted upstream of exon 1G and a floxed neo cassette was inserted downstream of exon 3 via homologous recombination. (J:143527, J:163272)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Mice Carrying this Mutation:

16 assay results
2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Gata2 Mutation:	30 strains or lines available

References

Original:	J:143527 Kala K, et al., Gata2 is a tissue-specific post-mitotic selector gene for midbrain GABAergic neurons. Development. 2009 Jan;136(2):253-62
All:	14 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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