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Tg(ACTA1-rtTA,tetO-cre)102Monk
Transgene Detail
Summary
Symbol: Tg(ACTA1-rtTA,tetO-cre)102Monk
Name: transgene insertion 102, Douglas Monks
MGI ID: MGI:4818775
Synonyms: HSA-rtTA/TRE-Cre, TRE-Cre
Transgene: Tg(ACTA1-rtTA,tetO-cre)102Monk  Location: unknown  
Alliance: Tg(ACTA1-rtTA,tetO-cre)102Monk page
Transgene
origin
Strain of Origin:  (C57BL/6 x C3H)F2
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase, Transactivator)
Inducer:    doxycycline/tetracycline
Mutation:    Insertion
 
Tg(ACTA1-rtTA,tetO-cre)102Monk expression driven by 1 gene
 
Mutation details: A transgenic construct containing cre recombinase under the control of the tetracycline-responsive regulatory element (tetO) and a second transgenic construct containing rtTA, under the control of the human ACTA1, actin, alpha 1, skeletal muscle promoter were coinjected into fertilized (C57BL/6 X C3H)F2 mouse eggs. Founder line 102 was subsequently established. Female founder animals were bred to wildtype C57BL/6J mice. (J:159973)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: ACTA1 (human)
Summary of all recombinase alleles driven by ACTA1.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:159973 Rao P, et al., A tetracycline-inducible and skeletal muscle-specific Cre recombinase transgenic mouse. Dev Neurobiol. 2009 May;69(6):401-6
All:  37 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory