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Tg(Lck-cre)#Nik
Transgene Detail
Summary
Symbol: Tg(Lck-cre)#Nik
Name: transgene insertion, Nigel Killeen
MGI ID: MGI:4819511
Synonyms: Dlck-cre, dLck-iCre
Transgene: Tg(Lck-cre)#Nik  Location: unknown  
Alliance: Tg(Lck-cre)#Nik page
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA/2)F2
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Lck-cre)#Nik expression driven by 1 gene
 
Mutation detailsThis transgene expresses cre recombinase under the control of the distal Lck promoter. This transgene is expressed in T cells primarily after Tcra locus rearrangement and the cells have reached the TCRhi stage of development. Lines 3778, 3779, and 3385. The symbol # denotes that no line number was specified or lines were pooled. (J:73479, J:99042)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Lck (species not specified)
Summary of all recombinase alleles driven by Lck.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:161995 Lee K, et al., Mammalian target of rapamycin protein complex 2 regulates differentiation of Th1 and Th2 cell subsets via distinct signaling pathways. Immunity. 2010 Jun 25;32(6):743-53
All:  36 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory