Tg(TRP53*R72P)7Dgj
Transgene Detail
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| Symbol: |
Tg(TRP53*R72P)7Dgj |
| Name: |
transgene insertion 7, David G Johnson |
| MGI ID: |
MGI:4819620 |
| Synonyms: |
p53P #7 |
| Transgene: |
Tg(TRP53*R72P)7Dgj Location: unknown
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| Alliance: |
Tg(TRP53*R72P)7Dgj page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutations: |
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Insertion, Single point mutation
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Tg(TRP53*R72P)7Dgj expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
TP53 (7157) |
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Transgene codes for a protein with an arginine to proline mutation. |
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Mutation details: The transgene contains human BAC 66H22 in which TRP53 was mutated to code a proline at position 72 instead of arginine. Both amino acids are polymorphic variants observed in humans. Line 7 was generated.
(J:162466)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:162466 Zhu F, et al., Mouse models for the p53 R72P polymorphism mimic human phenotypes. Cancer Res. 2010 Jul 15;70(14):5851-9 |
| All: |
3 reference(s) |
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Analysis Tools
