Tg(Fabp1-cre-GH1)1Jig
Transgene Detail
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Symbol: |
Tg(Fabp1-cre-GH1)1Jig |
Name: |
transgene insertion 1, Jeffrey I Gordon |
MGI ID: |
MGI:4820575 |
Synonyms: |
Fabpl-596 to +21Cre-hGH |
Transgene: |
Tg(Fabp1-cre-GH1)1Jig Location: unknown
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Alliance: |
Tg(Fabp1-cre-GH1)1Jig page
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Transgene Type: |
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Transgenic (Recombinase) |
Mutation: |
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Insertion
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Tg(Fabp1-cre-GH1)1Jig expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
Not Specified |
Fabp1 |
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Mutation details: A 1.0 kb fragment encoding cre recombinase was placed between nucleotides -596 to +21 of the rat Fabp1 and nucleotides +3 to +2150 of the human growth hormone gene (hGH; GH1). The purified fragment and injected into FVB/N oocytes. RNase protection assays in 8-week old mice demonstrated cre mRNA expression levels in small intestine (high in proximal half, lower in distal portion) and cecum (moderate) with barely detectable levels in the colon. Expression was also detected in the liver.
(J:65809)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Fabp1
(species not specified)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:65809 Wong MH, et al., Genetic mosaic analysis based on cre recombinase and navigated laser capture microdissection. Proc Natl Acad Sci U S A. 2000 Nov 7;97(23):12601-6 |
All: |
1 reference(s) |
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