Tg(FBN1*C1663R)F2Hcd
Transgene Detail
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Symbol: |
Tg(FBN1*C1663R)F2Hcd |
Name: |
transgene insertion F2, Harry C Dietz |
MGI ID: |
MGI:4820739 |
Synonyms: |
Tg(mut3) |
Transgene: |
Tg(FBN1*C1663R)F2Hcd Location: unknown
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Alliance: |
Tg(FBN1*C1663R)F2Hcd page
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Germline Transmission: |
Earliest citation of germline transmission:
J:91349
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Parent Cell Line: |
J1 (ES Cell)
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Strain of Origin: |
129S4/SvJae
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(FBN1*C1663R)F2Hcd expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
FBN1 (2200) |
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Mutation details: The transgene is composed of a YAC containing the full-length C1663R mutant human fibrillin 1 gene, including the promoter. Line F2 was generated.
(J:91349)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:91349 Judge DP, et al., Evidence for a critical contribution of haploinsufficiency in the complex pathogenesis of Marfan syndrome. J Clin Invest. 2004 Jul;114(2):172-81 |
All: |
1 reference(s) |
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