Mks1<avc6> Chemically induced Allele Detail MGI Mouse (MGI:4821832)

Mks1^avc6
Chemically induced Allele Detail

Summary

Symbol:	Mks1^avc6
Name:	MKS transition zone complex subunit 1; atrioventricular canal 6
MGI ID:	MGI:4821832
Gene:	Mks1 Location: Chr11:87744041-87754629 bp, + strand Genetic Position: Chr11, 52.24 cM
Alliance:	Mks1^avc6 page

Mutation
origin

Strain of Origin:

C57BL/6J

Mutation
description

Allele Type:		Chemically induced (ENU) (Null/knockout)
Mutation:		Single point mutation
		Mutation details: The causative mutation is a nonsense mutation, C-to-T transition at g.87853328. The C-to-T transition results in an arginine being converted to a premature stop codon, p.Arg27. (J:237132*)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Disease models

Expression

In Mice Carrying this Mutation:

3 assay results

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Mks1 Mutation:	29 strains or lines available

References

Original:	J:163196 Kamp A, et al., Genome-wide identification of mouse congenital heart disease loci. Hum Mol Genet. 2010 Aug 15;19(16):3105-13
All:	2 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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