Gene Expression Data
Assay Details
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Assay
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Reference:
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J:161948
Iwamoto R, et al., HB-EGF function in cardiac valve development requires interaction with heparan sulfate proteoglycans. Development. 2010 Jul;137(13):2205-14
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:4821872
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Gene symbol:
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Hbegf
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Gene name:
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heparin-binding EGF-like growth factor
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
S1a:
(close  )
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Genetic Background:
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B6.Cg-Hbegftm1.1Mek
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Mutant Allele(s):
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Hbegftm1.1Mek/Hbegf+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: endocardial cushion |
Present |
Single cells |
S1_A
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Expression is present in the endocardium of the cardiac cushion in the outflow tract valves.
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Specimen
S1b:
(close )
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Genetic Background:
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B6.Cg-Hbegftm1.1Mek
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Mutant Allele(s):
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Hbegftm1.1Mek/Hbegf+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: endocardial cushion |
Present |
Single cells |
S1_B
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Expression is present in the endocardium of the cardiac cushion in the atrio-ventricular valves.
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Specimen
S1c:
(close )
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Genetic Background:
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B6.Cg-Hbegftm1.1Mek
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Mutant Allele(s):
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Hbegftm1.1Mek/Hbegf+
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: endocardial cushion |
Present |
Regionally restricted |
S1_C
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Expression is restricted to the contact site, where the endocardia face each other in the outflow tract valves.
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Specimen
S1d:
(close )
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Genetic Background:
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B6.Cg-Hbegftm1.1Mek
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Mutant Allele(s):
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Hbegftm1.1Mek/Hbegf+
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Specimen
S1e:
(close )
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Genetic Background:
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B6.Cg-Hbegftm1.1Mek
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Mutant Allele(s):
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Hbegftm1.1Mek/Hbegf+
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: endocardial tissue |
Present |
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S1_E
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Expression is detected exclusively in the endocardium, in this case in the outflow tract valves and surrounding cells. It is not present in the mesenchyme.
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Specimen
S1f:
(close )
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Genetic Background:
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B6.Cg-Hbegftm1.1Mek
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Mutant Allele(s):
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Hbegftm1.1Mek/Hbegf+
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: endocardial tissue |
Present |
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S1_F
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Expression is detected exclusively in the endocardium, in this case in the atrio-ventricular canal valves and surrounding cells. It is not present in the mesenchyme.
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Specimen
S1g:
(close )
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Genetic Background:
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B6.Cg-Hbegftm1.1Mek
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Mutant Allele(s):
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Hbegftm1.1Mek/Hbegf+
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: endocardial tissue |
Present |
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S1_G
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Expression is detected exclusively in the endocardium, in this case in the outflow tract valves and surrounding cells. It is not present in the mesenchyme.
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Specimen
S1h:
(close )
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Genetic Background:
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B6.Cg-Hbegftm1.1Mek
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Mutant Allele(s):
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Hbegftm1.1Mek/Hbegf+
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: endocardial tissue |
Present |
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S1_H
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Expression is detected exclusively in the endocardium, in this case in the atrio-ventricular canal valves and surrounding cells. It is not present in the mesenchyme.
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Specimen
S1i:
(close )
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Genetic Background:
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B6.Cg-Hbegftm1.1Mek
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Mutant Allele(s):
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Hbegftm1.1Mek/Hbegf+
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS25: endocardial tissue |
Present |
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S1_I
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Expression is detected exclusively in the endocardium, in this case in the outflow tract valves and surrounding cells. It is not present in the mesenchyme.
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Specimen
S1j:
(close )
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Genetic Background:
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B6.Cg-Hbegftm1.1Mek
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Mutant Allele(s):
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Hbegftm1.1Mek/Hbegf+
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS25: endocardial tissue |
Present |
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S1_J
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Expression is detected exclusively in the endocardium, in this case in the atrio-ventricular canal valves and surrounding cells. It is not present in the mesenchyme.
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Analysis Tools
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