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Tg(KRT18-cre/ERT2)23Blpn
Transgene Detail
Summary
Symbol: Tg(KRT18-cre/ERT2)23Blpn
Name: transgene insertion 23, Cedric Blanpain
MGI ID: MGI:4821951
Synonyms: K18-CREER
Transgene: Tg(KRT18-cre/ERT2)23Blpn  Location: unknown  
Alliance: Tg(KRT18-cre/ERT2)23Blpn page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(KRT18-cre/ERT2)23Blpn expression driven by 1 gene
 
Mutation details: A fragment encoding cre recombinase fused to a modified estrogen receptor ligand-binding domain (ERT2) was cloned into a vector containing the human KRT18 promoter. The construct was injected into fertilized oocytes to generated transgenic mice. Two lines were obtained. Line 23 was used in the original reference. (J:163216)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: KRT18 (human)
Summary of all recombinase alleles driven by KRT18.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:163216 Van Keymeulen A, et al., Epidermal progenitors give rise to Merkel cells during embryonic development and adult homeostasis. J Cell Biol. 2009 Oct 5;187(1):91-100
All:  9 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory