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Fcrlbtm1Pdb
Targeted Allele Detail
Summary
Symbol: Fcrlbtm1Pdb
Name: Fc receptor-like B; targeted mutation 1, Peter D Burrows
MGI ID: MGI:4838081
Gene: Fcrlb  Location: Chr1:170734842-170740510 bp, - strand  Genetic Position: Chr1, 77.56 cM
Alliance: Fcrlbtm1Pdb page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:165408
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: Exons 1, 2 and a portion of 3 along with a 2-kb promoter region were replaced with the neomycin gene by homologous recombination. (J:165408)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fcrlb Mutation:  24 strains or lines available
References
Original:  J:165408 Masuda K, et al., Defining the immunological phenotype of Fc receptor-like B (FCRLB) deficient mice: Confounding role of the inhibitory FcgammaRIIb. Cell Immunol. 2010;266(1):24-31
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory