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Tg(Foxn4-icre)1Smal
Transgene Detail
Summary
Symbol: Tg(Foxn4-icre)1Smal
Name: transgene insertion 1, Stavros Malas
MGI ID: MGI:4838412
Synonyms: Foxn4-iCre
Transgene: Tg(Foxn4-icre)1Smal  Location: unknown  
Alliance: Tg(Foxn4-icre)1Smal page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Foxn4-icre)1Smal expression driven by 1 gene
 
Mutation detailsTransgenic mice were generated from a BAC in which exon 1 of the Foxn4 locus had been replaced with the coding sequence of codon-improved cre (icre) by homologou recombination. An frt-flanked selection cassette (kanamycin-resistance gene driven by the prokaryotic EM7 promoter) followed the icre sequence and was excised by Flp-recombination in bacteria during recombineering. Three founder lines were generated by pronuclear injection of the final 150 kb construct, with the line providing the most robust combination was selected for further study. No line numbers were specified in the reference. (J:164670)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Foxn4 (species not specified)
Summary of all recombinase alleles driven by Foxn4.
 

Expression
In Mice Carrying this Mutation: 12 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:164670 Panayi H, et al., Sox1 is required for the specification of a novel p2-derived interneuron subtype in the mouse ventral spinal cord. J Neurosci. 2010 Sep 15;30(37):12274-80
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory