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Tg(Itga2b-cre)AParl
Transgene Detail
Summary
Symbol: Tg(Itga2b-cre)AParl
Name: transgene insertion A, Roberto Parrilla
MGI ID: MGI:4839352
Synonyms: malphaIIb-cre (A)
Transgene: Tg(Itga2b-cre)AParl  Location: unknown  
Alliance: Tg(Itga2b-cre)AParl page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Itga2b-cre)AParl expression driven by 1 gene
 
Mutation details: A 4.14 kb fragment containing the Itga2b regulatory region linked to cre cDNA and the SV40 polyA signal was purified and injected into fertilized FVB/N oocytes. Four founders were identified (A,B,C,D). RT-PCR amplified mRNA only in megakaryocytes. Cre activity was identified in megakaryocytes from only two lines A and B. (J:164716)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Itga2b (species not specified)
Summary of all recombinase alleles driven by Itga2b.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:164716 Nowakowski A, et al., Megakaryocyte gene targeting mediated by restricted expression of recombinase Cre. Thromb Haemost. 2010 Oct 12;105(1)
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory