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Tg(Pdx1-cre)PBMga
Transgene Detail
Summary
Symbol: Tg(Pdx1-cre)PBMga
Name: transgene insertion PB, Maureen A Gannon
MGI ID: MGI:4839473
Synonyms: Pdx1PBCre
Transgene: Tg(Pdx1-cre)PBMga  Location: unknown  
Alliance: Tg(Pdx1-cre)PBMga page
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA/2)F1
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Pdx1-cre)PBMga expression driven by 1 gene
 
Mutation detailsA 1 kb Pst2-BstEI fragment (Pdx1) containing areas I and II of the Pdx1 gene was fused to the Hsp68 minimal promoter to drive expression of a cre/hGH fusion cDNA. One line was generated. (J:72023, J:122333)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Pdx1 (species not specified)
Summary of all recombinase alleles driven by Pdx1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:122333 Wiebe PO, et al., Ptf1a binds to and activates area III, a highly conserved region of the Pdx1 promoter that mediates early pancreas-wide Pdx1 expression. Mol Cell Biol. 2007 Jun;27(11):4093-104
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory