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Tg(Pdx1-cre)XBMga
Transgene Detail
Summary
Symbol: Tg(Pdx1-cre)XBMga
Name: transgene insertion XB, Maureen A Gannon
MGI ID: MGI:4839475
Synonyms: Pdx1XBCre
Transgene: Tg(Pdx1-cre)XBMga  Location: unknown  
Alliance: Tg(Pdx1-cre)XBMga page
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA/2)F1
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Pdx1-cre)XBMga expression driven by 1 gene
 
Mutation detailsA 1 kb XhoI-BglII fragment (Pdx1) of the Pdx1 gene fused to the Hsp68 minimal promoter was used to drive expression of a cre recombinase expression cassette. Four founders were generated that displayed similar cre-mediated recombination when crossed to reporter (R26R) mice. (J:72023, J:122333)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Pdx1 (species not specified)
Summary of all recombinase alleles driven by Pdx1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:122333 Wiebe PO, et al., Ptf1a binds to and activates area III, a highly conserved region of the Pdx1 promoter that mediates early pancreas-wide Pdx1 expression. Mol Cell Biol. 2007 Jun;27(11):4093-104
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory