Emg1<tm1Hdin> Targeted Allele Detail MGI Mouse (MGI:4839753)

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Emg1^tm1Hdin
Targeted Allele Detail

Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Summary

Symbol:	Emg1^tm1Hdin
Name:	EMG1 N1-specific pseudouridine methyltransferase; targeted mutation 1, Hao Ding
MGI ID:	MGI:4839753
Gene:	Emg1 Location: Chr6:124681344-124689118 bp, - strand Genetic Position: Chr6, 59.17 cM
Alliance:	Emg1^tm1Hdin page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:165972
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation
description

Allele Type:		Targeted (Null/knockout, Reporter)
Mutations:		Insertion, Intragenic deletion
		Mutation details: Exons 2 through 6 were replaced with a splice acceptor, IRES, and beta-geo cassette. Whole mount in situ confirmed beta-galactosidase activity. (J:165972)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Mice Carrying this Mutation:	30 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Emg1 Mutation:	23 strains or lines available

References

Original:	J:165972 Wu X, et al., EMG1 is essential for mouse pre-implantation embryo development. BMC Dev Biol. 2010;10:99
All:	1 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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