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Sufutm1Hui
Targeted Allele Detail
Summary
Symbol: Sufutm1Hui
Name: SUFU negative regulator of hedgehog signaling; targeted mutation 1, Chi-chung Hui
MGI ID: MGI:4840420
Synonyms: Sufufl, Sufuflox, SuFuloxP
Gene: Sufu  Location: Chr19:46385335-46477243 bp, + strand  Genetic Position: Chr19, 38.85 cM
Alliance: Sufutm1Hui page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:166285
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    Exons 4-8 were surrounded by loxP sites. A neomycin selection cassette was inserted as well. (J:166285)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 79 assay results
5 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sufu Mutation:  59 strains or lines available
References
Original:  J:166285 Pospisilik JA, et al., Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate. Cell. 2010 Jan 8;140(1):148-60
All:  26 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory