Tg(Spo11-cre)D5Mpel
Transgene Detail
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| Symbol: |
Tg(Spo11-cre)D5Mpel |
| Name: |
transgene insertion D5, Manuela Pellegrini |
| MGI ID: |
MGI:4850038 |
| Synonyms: |
Spo11Cre, Spo11-IRES-Cre |
| Transgene: |
Tg(Spo11-cre)D5Mpel Location: unknown
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| Alliance: |
Tg(Spo11-cre)D5Mpel page
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| Strain of Origin: |
BALB/c x C57BL/6
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| Transgene Type: |
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Transgenic (Recombinase) |
| Mutation: |
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Insertion
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Tg(Spo11-cre)D5Mpel expression driven by
1 gene
Transgene expression driven by:
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Mutation details: The BAC RP23-20N4 containing the entire Spo11 locus (including 188kb of sequence upstream of the initiation codon and 57kb downstream of the stop codon) was engineered by homologous recombination to insert an IRES-cre-(Frt-flanked) neo fragment immediately downstream of the stop codon. The neo was subsequently removed by Flp in bacteria. The modified BAC was injected into the pronuclei of fertilized eggs. Two named lines, D5 and H9, were generated and studied further.
(J:166888)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Spo11
(mouse)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:166888 Pellegrini M, et al., Targeted JAM-C deletion in germ cells by Spo11-controlled Cre recombinase. J Cell Sci. 2011 Jan 1;124(Pt 1):91-9 |
| All: |
4 reference(s) |
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Analysis Tools
