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Tmf1tm1Unir
Targeted Allele Detail
Summary
Symbol: Tmf1tm1Unir
Name: TATA element modulatory factor 1; targeted mutation 1, Uri Nir
MGI ID: MGI:4867389
Gene: Tmf1  Location: Chr6:97129958-97156083 bp, - strand  Genetic Position: Chr6, 44.89 cM
Alliance: Tmf1tm1Unir page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:166798
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe 3' portion of exon 2 was replaced with a lacZ gene and floxed neo cassette. The absence of protein expression was confirmed by western blot on testis extracts. (J:166798)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tmf1 Mutation:  45 strains or lines available
References
Original:  J:166798 Lerer-Goldshtein T, et al., TMF/ARA160: A key regulator of sperm development. Dev Biol. 2010 Dec 1;348(1):12-21
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory