Tg(Slc32a1-cre)2.1Hzo
Transgene Detail
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| Symbol: |
Tg(Slc32a1-cre)2.1Hzo |
| Name: |
transgene insertion 2.1, Huda Y Zoghbi |
| MGI ID: |
MGI:4867735 |
| Synonyms: |
Tg2.1, Viaat-Cre |
| Transgene: |
Tg(Slc32a1-cre)2.1Hzo Location: unknown
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| Alliance: |
Tg(Slc32a1-cre)2.1Hzo page
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| Transgene Type: |
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Transgenic (Recombinase) |
| Mutation: |
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Insertion
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Tg(Slc32a1-cre)2.1Hzo expression driven by
1 gene
Transgene expression driven by:
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Mutation details: BAC RP23-392P11 containing the Slc32a1 (Viaat) locus was modified by homologous recombination by inserting a Cre-recombinase sequence followed by a stop codon and a polyadenylation sequence downstream of the start codon of the Slc32a1 (or Viaat) gene. After linearization, the BAC only contained Viaat and the truncated coding sequence of the actin-related protein 5 homolog (Actr5) gene. This modified 109 kb BAC was microinjected into fertilized FVB/N oocytes. Transgenic animals have similar expression levels of Slc32a1 and Actr5 to wild type mice. Founder line 2.1 was analyzed and propagated.
(J:166851)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Slc32a1
(mouse)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:166851 Chao HT, et al., Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes. Nature. 2010 Nov 11;468(7321):263-9 |
| All: |
32 reference(s) |
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Analysis Tools
