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Ripply3tm1Sjt
Targeted Allele Detail
Summary
Symbol: Ripply3tm1Sjt
Name: ripply transcriptional repressor 3; targeted mutation 1, Shinji Takada
MGI ID: MGI:4880754
Gene: Ripply3  Location: Chr16:94129281-94137794 bp, + strand  Genetic Position: Chr16, 55.17 cM, cytoband C4
Alliance: Ripply3tm1Sjt page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:167713
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: Exons 1 - 3 were replaced with an IRES-lacZ-pgk-neo cassette via homologous recombination. RT-PCR analysis confirmed the absence of expression in homozygous embryos at E9.5. (J:167713)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 4 assay results
In Structures Affected by this Mutation: 17 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ripply3 Mutation:  9 strains or lines available
References
Original:  J:167713 Okubo T, et al., Ripply3, a Tbx1 repressor, is required for development of the pharyngeal apparatus and its derivatives in mice. Development. 2011 Jan;138(2):339-48
All:  5 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory