Summary | Transgene origin | Transgene description | Expression | Recombinase activity | Phenotypes | Tumor data | Find Mice (IMSR) | References

Symbol:	Tg(Wnt7a-EGFP/cre)#Bhr
Name:	transgene insertion, Richard R Behringer
MGI ID:	MGI:4882135
Synonyms:	Tg(Wnt7a-EGFP/cre)#Ksk, Wnt7a-Cre
Transgene:	Tg(Wnt7a-EGFP/cre)#Bhr  Location: unknown
Alliance:	Tg(Wnt7a-EGFP/cre)#Bhr page

Strain of Origin:

(C57BL/6 x SJL)F1

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Wnt7a-EGFP/cre)#Bhr expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Wnt7a (MGI:98961)   Mutation details: An IRES-EGFP/cre with an FRT-flanked kanamycin selection cassette was targeted to exon 2 of the Wnt7a locus in BAC RP23-53E13. After homologous recombination in EL250 cells, correctly targeted clones were selected and FRT recombination was induced in cells by arabinose to remove the kanamycin cassette. The linearized BAC was injected into pronuclei of B6SJLF1 hybrid zygotes. Mice express an EGFP-cre fusion gene product. No line numbers are available. (J:167551, J:191769)

Activity:	Tissue activity of this recombinase allele
Driver:	Wnt7a (mouse) Summary of all recombinase alleles driven by Wnt7a. Comparative matrix view of recombinase activities Alliance mouse Wnt7a gene page

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

25 assay results 3 RNA-Seq or microarray experiment(s)

List all tumor models in MMHCdb carrying Tg(Wnt7a-EGFP/cre)#Bhr

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:167551 Winuthayanon W, et al., Uterine epithelial estrogen receptor alpha is dispensable for proliferation but essential for complete biological and biochemical responses. Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19272-7
All:	31 reference(s)