Rag2<tm1.1Flv> Targeted Allele Detail MGI Mouse (MGI:4887836)

Rag2^tm1.1Flv
Targeted Allele Detail

Summary

Symbol:	Rag2^tm1.1Flv
Name:	recombination activating gene 2; targeted mutation 1.1, Richard A Flavell
MGI ID:	MGI:4887836
Gene:	Rag2 Location: Chr2:101455063-101462874 bp, + strand Genetic Position: Chr2, 53.87 cM
Alliance:	Rag2^tm1.1Flv page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:168303
Parent Cell Line:	V17 (ES Cell)
Strain of Origin:	BALB/cAnNTac x 129S4/SvJae

Mutation
description

Allele Type:		Targeted (Null/knockout)
Mutation:		Insertion
		Mutation details: A floxed PGK-neomycin cassette replaced the coding region. Cre-mediated recombination removed the neo cassette. (J:168303)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 6 strains available Cell Lines: 0 lines available
Carrying any Rag2 Mutation:	119 strains or lines available

Notes

Originally generated in conjunction with Il2rg^tm1.1Flv.

References

Original:	J:168303 Song J, et al., A mouse model for the human pathogen Salmonella typhi. Cell Host Microbe. 2010 Oct 21;8(4):369-76
All:	93 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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